2024, Vol. 7, Issue 2, Part C

Author(s)
Cindy Christella Chandra, Sukmawati Tansil Tan, Winnia Tanely, Cindy Christian, and Diana Heny

Abstract
Vitiligo is a chronic skin disorder characterized by white macules due to melanocyte destruction in the skin and mucosa. The disease not only has a negative impact on aesthetics, but also self-confidence and psycho-social well-being. While there are several treatment options to stop depigmentation and stimulate repigmentation, there is no specific or gold standard treatment that is highly satisfactory. This case report presents a 19-year-old male who came to the dermatology clinic with milky white patches on the right side of his face, cheeks and nose since one month prior. Initially, the patches were small, then expanded and multiplied. On dermatologic examination, multiple depigmented macula-plaques, with firm borders, irregular edges, unilateral distribution, and varying in shape and size were found. The patient was diagnosed as Segmental Vitiligo with VETF 7, 6. The patient was treated with dermapen (microneedling therapy) every 2 weeks for 9 months by applying 0.3 cc of 5% CM-WJMSCs (Conditioned Medium-Wharton's jelly-Mesenchymal Stem Cells) serum to the entire lesion area. The serum was also applied 2 times a day daily at home. At follow-up, it was found that the lesions slowly started to repigment with VETF 5.6. Secretome has many functions especially immunomodulatory which could modify the immune system of vilitigo. In this patient, the therapy produced good results without hyperpigmentation in the lesions. Thus, secretome might be a good treatment choice for vitiligo.

DOI: https://doi.org/10.33545/26649411.2024.v7.i2c.213

Pages: 147-149 | Views: 86 | Downloads: 34