Lucio's phenomenon (LP) is a rare leprosy reaction characterized by severe necrosis of the skin. LP is a variant of type II leprosy reaction by the involvement of immune complexes. LP is usually found in Mexico and Central America. This reaction is especially found in diffuse non-nodular lepromatous leprosy who have not received or completed leprosy treatment.
Case: A 36 years woman with newly diagnosed Lucio’s phenomenon after initially being misdiagnosed with fungal infection for several months.
Discussion: In clinically, LP may mimic other diseases such as mycosis and allergic reaction.Until now there is no consensus regarding LP treatment and combination MDT-MB and systemic corticosteroids are the options in this case.
Conclusion: A proper history, physical examination, and histopathology are important diagnostic approaches to avoid misdiagnosis or underdiagnosis in LP cases especially in leprosy endemic regions. The combination of MDT-MB and systemic corticosteroids in LP gives a good response.