International Journal of Dermatology, Venereology and Leprosy Sciences
2021, Vol. 4, Issue 2, Part A
Role of biochip indirect immunofluorescence assay in diagnosis of autoimmune vesicobullous disorders in a tertiary care setting
Subadharshini B, Kaviarasan PK, Kannambal K and Poorana B
Aim: To evaluate the role of BIOCHIP mosaic based immunofluorescence test in the screening and diagnosis of autoimmune bullous disorsders. Results: Results of DIF and BIOCHIP were compared with clinical diagnosis. The sensitivity of DIF was 99% in all epidermal and subepidermal bullous diseases. The sensitivity of BIOCHIP in the diagnosis of pemphigus vulgaris, bullous pemphigoid, pemphigus foliaceus was almost 100% and comparable with that of DIF. Conclusion: Thus the sensitivity and diagnostic accuracy of BIOCHIP is comparable with DIF making it a more effective practical screening tool for patients with suspected AIBD. Thus, BIOCHIP can be used as first line tool in the diagnosis of autoimmune bullous disorders.
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How to cite this article:
Subadharshini B, Kaviarasan PK, Kannambal K, Poorana B. Role of biochip indirect immunofluorescence assay in diagnosis of autoimmune vesicobullous disorders in a tertiary care setting. Int J Dermatol Venereology Leprosy Sci 2021;4(2):93-96. DOI: 10.33545/26649411.2021.v4.i2a.102