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International Journal of Dermatology, Venereology and Leprosy Sciences

International Journal of Dermatology, Venereology and Leprosy Sciences

2019, Vol. 2, Issue 2, Part A

A comparative evaluation of benzoyl peroxide & clindamycin versus tretinoin and clindamycin in cases of acne vulgaris
Author(s)
Roohi Sharma, Reeta Gupta and Pavan Malhotra
Abstract
Background: Acne vulgaris is a chronic, self-limiting, inflammatory disease of the pilosebaceous unit characterized by pleomorphic lesions like comedones, erythromatous papules, pustules, cysts and nodules. The present study compared benzoyl peroxide & clindamycin versus tretinoin and clindamycin in cases of Acne vulgaris.
Materials & Methods: 104 cases of Acne vulgaris were divided into 2 groups of 52 each. Group I patients were given benzoyl peroxide 2.5% gel once daily at bedtime and clindamycin 1% gel once daily topically and group II patients were prescribed tretinoin 0.025% and clindamycin 1% gel once daily at bedtime topically.
Results: There were 20 males and 32 females in group I and 18 males and 34 females in group II. The mean number of inflammatory lesions at baseline in group I was 12.4, in group II was 14, after 4 weeks was 4.7 and 7.2 in group I and II respectively, after 8 weeks was 1.2 and 3.4 in group I and II respectively and after 12 weeks was 0 and 2.1 in group I and group II respectively. The difference was significant (P< 0.05).
Conclusion: Combination of Benzoyl peroxide 2.5% & Clindamycin 1% was effective as compared to Tretinoin 0.025% & Clindamycin 1% in patients of Acne vulgaris.
Pages: 25-27 | Views: 226 | Downloads: 121
How to cite this article:
Roohi Sharma, Reeta Gupta, Pavan Malhotra. A comparative evaluation of benzoyl peroxide & clindamycin versus tretinoin and clindamycin in cases of acne vulgaris. Int J Dermatol Venereology Leprosy Sci 2019;2(2):25-27. DOI: 10.33545/26649411.2019.v2.i2a.59
International Journal of Dermatology, Venereology and Leprosy Sciences