AbstractBackground: Adolescents and young adults often experience acne vulgaris, a condition affecting the sebaceous unit. Lifelong scarring from acne can take the shape of atrophic, hypertrophic, or keloid scars. No medical intervention can reverse the atrophying scars caused by acne; these scars are categorized as ice-pick, rolling, or boxcar scars.
Methods: A study using a randomized controlled open-label prospective design aimed to compare the effectiveness of microneedling, subcision, and 50% TCA CROSS as a combo therapy with microneedling and subcision alone. The study was carried out in the Department of Dermatology, Sambhram Institute of Medical Sciences, located in Kolar, Karnataka, India. The investigation was conducted from January 2018 to December 2019.
Results: The findings can be compared to those of prior studies that utilized diverse methodologies. Out of the 60 patients included in our study, 75 percent of them, who had an average age of 23, fell between the age ranges of 21 to 30. The majority of patients in Group 1 are between the ages ranges of 21 to 25, accounting for 77% of patients aged 21 to 30. Conversely, 71% of individuals in group 2 fell between the age ranges of 21 to 30. In a study conducted by Raza Hassan et al., the average age of the patients was 25.07 years, with the majority falling between the 26–30 year age brackets.
Conclusion: Based on this study, it can be inferred that acne vulgaris is a chronic inflammatory syndrome that affects the pilo sebaceous follicular unit. This is caused by the colonization of follicles by Propionibacterium acnes, increased production of sebum, and aberrant keratinization of the follicles.
