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International Journal of Dermatology, Venereology and Leprosy Sciences

International Journal of Dermatology, Venereology and Leprosy Sciences

2019, Vol. 2, Issue 1, Part A

A hospital based assessment of the effects of various topical agents in chronic plaque type psoriasis
Author(s)
Manoj Kumar Agarwala, Rohal Chandrakar and Riddhi Arora
Abstract
Aim: To determine the effect of various topical agents in chronic plaque type psoriasis.
Materials and Methods: The study was carried out on patients having chronic plaque type psoriasis vulgaris came to the Department of Dermatology, Chandulal Chandrakar Memorial Medical College, Durg, Chhattisgarh, India. Total 300 patients were enrolled and were divided into three groups comprising of 100 patients in each group. Group A patients were asked to apply ammonium lactate twice a day, Group B patients were asked to apply ammonium lactate in morning and clobetasol propionate in evening, Group C patients were asked to apply topical ammonium lactate in morning and calcipotriol in evening.
Results: Physician global assessment scale shows that in Group A, 39% patients had excellent response, 15% patients had good response, and 21% patients had fair response whereas 25% patients had poor response. In group B, 35% patients had excellent response, 29% patients had good response, and 17% patients had fair response whereas 19% patients had poor response. In group C, 31% patients had excellent response, 28% patients had good response, and 22% patients had fair response whereas 19% patients had poor response.
Conclusion: Combination therapy is effective, well tolerated with minimal side effects and better compliance was seen with patients. Ammonium lactate 12% can also be considered as one of the topical option as a monotherapy and also as a maintenance therapy.
Pages: 22-24 | Views: 28 | Downloads: 17
How to cite this article:
Manoj Kumar Agarwala, Rohal Chandrakar, Riddhi Arora. A hospital based assessment of the effects of various topical agents in chronic plaque type psoriasis. Int J Dermatol Venereology Leprosy Sci 2019;2(1):22-24. DOI: 10.33545/26649411.2019.v2.i1a.112
International Journal of Dermatology, Venereology and Leprosy Sciences